Biomarkers Which Inform Treatment

Searching for Qualitative Interactions

DNA orbit animated

Modern medicine has graduated from broad spectrum treatments to targeted therapeutics. New treatments attack specific genetic pathways which are only dysregulated in some smaller subset of patients with a disease. Unfortunately this subset is often poorly understood. Building/discovering biomarkers to characterize this subset is key to personalizing medicine.

Our goal in this project is to screen [potentially high dimensional] biomolecular features, to find those few that are clinically informative. This work combines aspects of statistics, computer science, and biomedical science.